Rang and Dale's Pharmacology / James M. Ritter, Rod Flower, Graeme Henderson, Yoon Kong Loke, David MacEwan, Humphrey P. Rang.
Material type: TextPublisher: Edinburgh : Elsevier, 2019Edition: Ninth editionDescription: xvi, 789 : color illustrations ; 28 cmContent type:- text
- still image
- unmediated
- volume
- 9780702074486
- 0702074489
- Rang & Dale's Pharmacology
- Pharmacology
- 615.1 23
- RM300 .R35 2019
Previous edition: Edinburgh: Elsevier Churchill Livingstone, 2016.
Includes bibliographical references and index.
Section 1: General principles. What is pharmacology? -- How drugs act: general principles -- How drugs act: molecular aspects -- How drugs act: cellular aspects excitation, contraction and secretion -- How drugs act: biopharmaceuticals and gene therapy -- Cell proliferation, apoptosis, repair and regeneration -- Cellular mechanisms: host defence -- Method and measurement in pharmacology -- Absorption and distribution of drugs -- Drug metabolism and elimination -- Pharmacokinetics -- Individual variation, pharmacogenomics and personalised medicine -- Section 2: Chemical mediators. Chemical mediators and the autonomic nervous system -- Cholinergic transmission -- Noradrenergic transmission -- 5-Hydroxytryptamine and the pharmacology of migraine -- Purines -- Local hormones 1: histamin and the biologically active lipids. -- Local hormones 2: peptides and proteins -- Cannabinoids -- Nitric oxide and related mediators -- Section 3: Drugs affecting major organ systems. The heart -- The vascular system -- Atherosclerosis and lipoprotein metabolism -- Haemostasis and thrombosis -- Haemopoietic system and treatment of anaemia -- Anti-inflammatory and immunosuppressant drugs -- Skin -- Respiratory system -- The kidney and urinary system -- The gastrointestinal tract -- The control of blood glucose and drug treatment of diabetes mellitus -- Obesity -- The pituitary and the adrenal cortex -- The thyroid -- The reproductive system -- Bone metabolism -- Section 4: Nervous system. Chemical transmission and drug action in the nervous system -- Amino acid transmitters -- Other transmitters and modulators -- Neurodegenerative diseases -- General anaesthetic agents -- Analgesic drugs -- Local anaesthetics and other drugs affecting sodium channels -- Anxiolytic and hypnotic drugs -- Antiepileptic drugs -- Antipsychotic drugs -- Antidepressant drugs --Psychoactive drugs -- Drug abuse and dependence -- Section 5: Drugs used for the treatment of infections and cancer. Basic principles of antimicrobial chemotherapy -- Antibacterial drugs -- Antiviral drugs -- Antifungal drugs -- Antiprotozoal drugs -- Anthelminthic drugs -- Anticancer drugs -- Section 6: Special topics. Harmful effects of drugs -- Lifestyle and drugs in sport -- Drug discovery and development.
"Comprehensive yet easy to use, Rang and Dale's Pharmacology has been providing core basic and clinical science information to students and healthcare practitioners worldwide for more than 25 years. The fully revised 9th Edition keeps you up to date with all that's new in the field, including new and emerging drugs and recent studies. From cover to cover, you'll progressively increase your knowledge of all relevant aspects of pharmacology, from a molecular understanding of receptors and drug actions through clinical uses of key groups of drugs"--Publisher's description.
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