Exploring immunology concepts and evidence Gordon MacPherson and Jon Austyn ; illustrations by Ruth Hammelehle

Includes bibliographical references and index

INTRODUCTION Introduction Immune Responses Infection and Immunity Immunopathology and Immunotherapy Exploring Immunology THE IMMUNE SYSTEM Introduction Host Defence Against Infection Anatomical Basis of Immunity Cellular Basis of Immunity Molecular Basis of Immunity Immune Responses and Disease INFECTION AND IMMUNITY Introduction Pathogens and Infectious Disease Host Defence Against Infection Infection and Immunity in Action Immunity and Vaccines FUNCTIONAL ANATOMY OF THE IMMUNE SYSTEM Introduction Natural Barriers Functional Anatomy of Innate Immunity Functional Anatomy of Adaptive Immunity Development of Blood Cells and Organs of Immunity Stem Cell and Gene Therapy INNATE IMMUNITY Introduction Induction of Innate Immunity "Tissue-Resident Cells" of Innate Immunity Recruited Effectors of Innate Immunity Haematopoiesis and Myeloid Cells Vaccines and Adjuvants T CELL-MEDIATED IMMUNITY Introduction Major Histocompatibility Complex and Antigen Presentation T Lymphocyte Activation Effector and Memory Functions of T Cells in Infection T Cell Development and Selection Adoptive Cell Therapy ANTIBODY-MEDIATED IMMUNITY Introduction Antibody Structure and Function B Cell Responses B Cell Memory, Antibodies and Long-Term Resistance to Re-Infection Cell Differentiation and Selection Therapeutic Antibodies IMMUNITY, DISEASE AND THERAPY Introduction What are the Mechanisms of Tissue Damage Caused by the Immune System? Why Do We Make Harmful Immune Responses to Harmless Antigens? Immunopathology and Therapy in Action Transplantation Immunology Tumour Immunity Conclusions ANSWERS TO THE QUESTIONS FURTHER STUDY QUESTIONS

21