TY  - BOOK
AU  - Kramer,Ijsbrand M.
TI  - Signal transduction
AV  - QP517.C45 
U1  - 571.7/4 23
PY  - 2016///]
CY  - London
PB  - Elsevier/Academic Press
KW  - Cellular signal transduction
KW  - Signal Transduction
KW  - Transduction du signal cellulaire
KW  - SCIENCE
KW  - Life Sciences
KW  - Cell Biology
KW  - bisacsh
KW  - fast
KW  - Signalen
KW  - gtt
KW  - Electronic books
KW  - NATCOLCK
N1  - Includes bibliographical references; Prologue : signal transduction from an historical perspective -- An introduction to signal transduction -- Regulation of muscle contraction by adrenoceptors -- Cholinergic signaling and muscle contraction -- Sensory signal processing; visual transduction and olfaction -- Intracellular calcium -- Bringing the signal into the nucleus : regulation of gene expression -- Nuclear receptors -- Protein kinase c in oncogenic transformation and cell polarity -- Regulation of cell proliferation by receptor tyrosine protein kinases -- Signal transduction to and from adhesion molecules -- WNT signaling and the regulation of cell adhesion and differentiation -- Activation of the innate immune system : the toll-like receptor-4 and signaling through ubiquitinylation -- Chemokines and traffic of white blood cells -- Activating the adaptive immune system : role of non-receptor tyrosine kinases -- Signaling through the insulin receptor : phosphoinositide 3-kinases and AKT -- TGF[beta] and signaling through receptor serine/threonine protein kinases -- Protein phosphatases -- Cell fate determination by notch
N2  - "A reference on cellular signaling processes, the third edition of Signal Transduction continues in the tradition of previous editions, in providing a historical overview of how the concept of stimulus-response coupling arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, growth factors and adhesion molecules. In a new chapter, an introduction to signal transduction, the book provides a concise overview of receptor mechanisms, from receptor -ligand interactions to post-translational modifications operational in the process of bringing about cellular changes. The phosphorylation process, from bacteria to men, is discussed in detail. Signal transduction third edition further elaborates on diverse signaling cascades within particular contexts such as muscle contraction, innate and adaptive immunity, glucose metabolism, regulation of appetite, oncogenic transformation and cell fate decision during development or in stem cell niches. The subjects have been enriched with descriptions of the relevant anatomical, histological, physiological or pathological condition."--Page 4 of cover
UR  - https://go.openathens.net/redirector/hse.ie?url=https%3a%2f%2fwww.clinicalkey.com%2fdura%2fbrowse%2fbookChapter%2f3-s2.0-C2011005860X
ER  -