TY  - BOOK
AU  - Jambhekar,Sunil S.
AU  - Breen,Philip J.
ED  - Royal Pharmaceutical Society of Great Britain.
TI  - Basic pharmacokinetics
SN  - 9780853699804
AV  - RM301.5 
PY  - 2012///
CY  - London
PB  - Pharmaceutical Press
KW  - Pharmacokinetics
KW  - Problems, exercises, etc
KW  - Drug Therapy
KW  - methods
N1  - Prev. ed.: 2009; Copyright held by the Royal Pharmaceutical Society of Great Britain; Includes bibliographical references (pages 453-460) and index; Introduction and overview -- Mathematical review -- Intravenous bolus administration (one-compartment model) -- Clearance concepts -- Drug absorption from the gastrointestinal tract -- Extravascular routes of drug administration -- Bioavilability/bioequivalence -- Factors affecting drug absorption : physicochemical factors -- Gastrointestinal absorption : role of the dosage form -- Continuous intravenous Infusion (one-compartment model) -- Multiple dosing: intravenous bolus administration -- Multiple dosing: extravascular routes of drug administration -- Two-compartment model -- Multiple intermittent infusions -- Nonlinear pharmacokinetics -- Drug interactions -- Pharmacokinetics and pharmacodynamics relationships -- Metabolite pharmacokinetics -- Pharmacokinetic data fitting -- Pharmacokinetics and pharmacodynamics of biotechnology drugs
ER  -