Brody's human pharmacology : mechanism-based therapeutics / [edited by] Lynn Wecker ; with David A. Taylor, Robert James Theobald, Jr.

Includes bibliographical references and index.

Section 1: Mechanisms of drug action and therapeutic principles. -- Introduction, terminology -- Pharmacodynamics: drug targets (receptors, enzymes, DNA, etc) -- Pharmacokinetics -- Pharmacogenomics -- Drug discovery, development, and regulation -- Section 2: Chemical mediators and drugs affecting autonomic and neuromuscular synapses. -- Introduction to the peripheral nervous systems and drugs for peripheral disorders -- Cholinergic drugs -- Muscarinic agonists and their clinical uses -- Muscarinic antagonists and their clinical uses -- Nicotinic agonists and their clinical uses -- Nicotinic antagonists and neuromuscular blocking drugs -- Adrenergic drugs -- Adrenergic agonists and their clinical uses -- Adrenergic antagonists and their clinical uses -- Section 3: Drug treatment for disorders affecting the central nervous system. Introduction to the CNS and drugs affecting the brain -- Neurodegenerative disorders -- Drug therapy for Alzheimer's disease and other cognitive disorders/dementias -- Pharmacotherapy of basal ganglia disorders: Parkinson's disease and Huntington's disease -- Drug therapy for psychoses and bipolar disorder -- Drug therapy for depression and anxiety -- Drug therapy for the management of attention deficit hyperactivity disorder -- Drug therapy for insomnia and the hypersomnias -- Drug therapy for managing obesity and eating disorders -- Treatment of seizure disorders -- Drug therapy to control spasticity disorders -- Ethanol, other alcohols, and drugs for alcohol use disorder -- Illicit psychoactive compounds and substance use disorder -- Section 4: Drug therapy for pain management. Introduction -- General anesthetics -- Local anesthetics -- Opioid analgesics -- Nonsteroidal anti-inflammatory agents and acetaminophen -- Cannabinoids -- Section 5: Treatment of inflammatory, allergic and immunologic disorders. Drug therapy for migraine headache -- Drug therapy for gout and hyperuricemia -- Drug treatment for allergic reactions -- Immunosuppressants for autoimmune disorders and organ transplantation -- Drug therapy for rheumatoid arthritis -- Section 6: Drug treatment for cardiovascular diseases. Introduction to the cardiovascular system and the regulation of blood pressure and heart rate -- Overview of hypertension management and drugs that decrease sympathetic tone -- Diuretics and drugs that affect volume and electrolyte content -- Drugs affecting the renin-angiotensin-aldosterone system -- Calcium channel blockers -- Vasodilators -- Drug therapy for hyperlipidemias and atherosclerotic cardiovascular disease -- Drug therapy for myocardial ischemia and angina pectoris -- Treatment of heart failure: cardiac glycosides, phosphodiesterase inhibitors and other agents -- Antiarrhythmic drugs -- Anticoagulant, antiplatelet and thrombolytic agents -- Drug therapy for hemophilia and the anemias

Section 7: Treatment of endocrine disorders. Introduction to endocrine pharmacology -- Treatment of hypothalamic and pituitary disorders -- Treatment of adrenalcorticosteroid disorders -- Female hormone regulation -- Androgens, antiandrogens and their clinical uses -- Drug therapy for the management of diabetes -- Drug therapy for the management of thyroid disorders -- Calcium regulating hormones and agents affecting bone -- Section 8: Chemotherapy. Infectious diseases -- Principles of antimicrobial use -- Bacterial cell wall synthesis inhibitors -- Inhibitors of protein synthesis -- Drugs that target DNA -- Antimycobacterial drugs and the treatment of tuberculosis and leprosy -- Drug therapy for resistant organisms -- Parasitic diseases -- Antifungal agents -- Antimalarial and other antiprotozoal agents -- Antihelmintics -- Viruses -- Drug therapy for non-HIV viral infections -- Drugs for HIV and related opportunistic infections -- Cancer -- Introduction and therapeutic principles -- Cytotoxic agents -- Targeted agents -- Section 9: Special considerations. Therapeutic use of hematopoietic growth factors, vitamins and minerals -- Gastrointestinal disorders and their treatment -- Pharmacological treatment of asthma and COPD -- The role of neutraceuticals and natural products -- Essentials of toxicology -- Therapeutic considerations for pregnant, pediatric, geriatric and obese individuals.

"Focusing on the essential aspects of pharmacology you need to know, Brody's Human Pharmacology, 6th Edition, keeps you fully up to date with all that's new in the field. Streamlined content, a new organizational approach, enhanced online components, and thoroughly updated information ensure your grasp of key concepts and prepare you for exams. Nearly 500 full-color illustrations explain important processes, while color-coded boxes for major drugs, therapeutic overviews, clinical problems, and trade names reinforce your mastery of the information"--Publisher's description

Online resource; title from electronic title page (ClinicalKey, viewed August 2, 2018).

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